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As we age, collagen production declines, which is why our skin gets saggy and more wrinkled. PLINEST™ is an ideal way to tackle ageing concerns suggested for prevention and maintaining patient's skin quality. It helps to remodel the skin resulting in a firmer, smoother and more radiant complexion.

PLINEST™ is an injectable product designed to improve skin quality, appearance, and elasticity. It contains polynucleotides, which are clinically proven to stimulate collagen production and improve bio-regeneration of the patient’s skin.

How Polynucleotides-HPT work…
When we inject polynucleotides-HPT ™ into the skin, they reach the cells called fibroblasts.

Fibroblasts are responsible for the formation of connective tissue through their ability to produce collagen, which helps maintain the skin’s firm structure.

Our main focus for PLINEST™ at EK Clinic is treating the eye area and also to treat hair loss alongside PRP.

Polynucleotides are highly-purified DNA molecules of natural extraction produced in Sanremo, Italy.

Procedure Time

30 minutes


A numbing cream will be applied before the treatment. You may experience some mild discomfort.

Risks & Recovery

There’s a low risk of short-term bruising but no downtime required.Your skin maybe slightly red and swollen immediately after the procedure, there is a minimal risk of brusing.


You’ll see results with just one treatment but these will continue to improve throughout your course, with best results seen a few weeks after your final session.

Price List


Plinest® Eye

£650 for a course of 3 treatments.

£250 for individual treatment

£225 for maintenance treatment (after a course)

Go Cardless

Save with us monthly or weekly towards your treatment plan. Contact us today for more information

Emma is extremely knowledgeable and experienced and always gives detailed, honest advice on what she thinks will give you the best outcome. I wouldn’t trust anyone with my face but Emma!

Lucy Kelly

Fantastic service from Tara! I highly recommend giving ek clinic a try if you are trying to make self improvements, the girls are all so friendly and welcoming.


Let's Talk

Arrange your complimentary consultation now so you can start to understand your potential treatment journey in the non-surgical aesthetics arena. Here at EK Clinic®, we offer face to face and virtual consultations to suit you. 

Whatever your concerns, our Aesthetic Medical Team will be able to give you advice on all things skin related especially ageing positively.


What is PLINEST™?

It is an injectable product designed to improve skin quality, appearance, and elasticity. It contains polynucleotides, which are clinically proven to stimulate collagen production and improve bio-regeneration of the skin.

Where does PLINEST™ treat?

We treat the eye area, not many treatments are suitable around the eye area but PLINEST® have developed a specific product to treat the eye and we are super excited to be able to offer it in clinic.

We also use PLINEST® to treat hair loss and this can be used inconjunction with our PRP treatment, read more about this here.

How many treatments will I need?

We recommend a course of 3 treatments, 14-21 days apart, to see optimal results.

How long do the results last?

After your course has finished, results are expected to last 6-9 months. Maintenance treatments are then advised.


Avoid touching the treated area for 6 hours after the treatment.
After that the area can be washed with a gentle cleanser.
Avoid make-up or cream on the treated area for 24 hours.
Avoid strenuous exercise and swimming to avoid risks of infection.
Avoid alcohol consumption for 24 hours before and after treatment.
Apply SPF50 for at least 7 days after your treatment.
Do not expose the treated area to intense heat (eg. Sauna, steam rooms, hot showers and sunbathing) or extreme cold.

How can I book?

Book online here. We recommend booking a consultation to discuss your bespoke treatment plan before having your treatment. However, there is often the opportunity for you to have the treatment on the day.

EK Recommendations

Remember - Healthy skin is a fundamental building block in the success of non-surgical treatment. We provide a range of medical grade cosmeceutical skincare to optimise your aesthetics treatment results. We only recommend products we use and believe in.


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